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2014 - Anélio Dias do Nascimento Júnior

MSc. Thesis

Author: Anélio Dias do Nascimento Júnior

Postgraduate Program in Pharmaceutical Sciences - State University of Maringá

Area of Knowledge: Pharmacognosy

Date of Defense: February 27, 2015

Advisor: Prof. Dr.  João Carlos Palazzo de Mello

Examination Board:  Profa. Dra. Áurea Regina Teles Pupulin

                            Profa. Dra. Jacqueline Nelisis Zanoni

 

Title: Spectrophotometric study of dynamised plant extracts

Abstract: Homeopathy had its foundations laid in the late eighteenth century. Evolved within their practices during the nineteenth century and continues to evolve day by day, but at a markedly slower pace. To understand the process many aspects are important, but the difficulty in its technological lead can not be ignored at least with regard to the drug. This is because of its unique pharmacological producing very dilute solutions. Thus, its quality control is not effective, despite significant efforts. Although the aim of this study was to evaluate the UV-Vis spectrophotometry as a tool for quality control of homeopathic medicines, the results can contribute to their knowledge more widely. For this, dynamized drugs obtained from mother tinctures of Arnica montana L., Matriarcaria chamomilla L. and Eupatorium perfoliatum L. were evaluated from 1CH to 30CH. The characterization by UV-Vis spectroscopy was performed using a reading between 190 and 450 nm using as a blank solution hydroethanol. The results show that no potency in any spectrum, was at least similar to the hydroethanol used as an inert ingredient in boosting and white as in reading. More importantly, the technique allows to differentiate the non-energized, the study medication each other and identify the first two potency of each.

Keywords: Dynamized drugs; quality control; ultra high dilutions; UV-Vis spectrophotometry; Arnica montana; Matriarcaria chamomilla; Eupatorium perfoliatum.

  

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